SSRIs Reveal New Potential Beyond Depression Treatment
Updated: 2024-05-31 20:44:45
SSRIs Reveal New Potential Beyond Depression Treatment Featured Neuroscience May 31, 2024 Summary : A new study uncovers a key biological process targeted by SSRIs , suggesting new clinical applications . The study found that SSRIs affect membrane trafficking in cells , which might explain their broader . effects Remarkably , a single dose of fluvoxamine in mice enabled drug delivery across the blood-brain barrier . This discovery could lead to SSRIs aiding in the delivery of drugs for conditions like . dementia Key : Facts SSRIs impact the ability of cells to transport materials via membrane . trafficking A single dose of fluvoxamine can facilitate drug delivery across the blood-brain barrier in . mice This finding suggests potential new uses for SSRIs in treating hard-to-reach conditions
Mediterranean Diet Cuts Mortality Risk by 23 in Women Featured Neuroscience May 31, 2024 Summary : Following a Mediterranean diet reduces the risk of all-cause mortality by 23 in U.S . women over 25 years . The diet’s benefits include lower cancer and cardiovascular mortality , linked to positive changes in metabolism , inflammation , and insulin resistance . Researchers analyzed biomarkers to understand these health improvements . The study highlights the dietâ s potential for long-term health . benefits Key : Fact The Mediterranean diet reduces all-cause mortality risk by 23 in U.S . . women Benefits include lower cancer and cardiovascular . mortality Positive changes in metabolism , inflammation , and insulin resistance explain the health . improvements Source : Brigham and Women’s
, Higher TBI Risk Found in Wealthier , Healthier Seniors Featured Neurology Neuroscience May 31, 2024 Summary : 13 of older adults are diagnosed with traumatic brain injury TBI often from ground-level falls . The study found that wealthier , healthier , and more active seniors have a higher risk of TBI , contrary to previous findings in younger populations . This research highlights the need for tailored post-TBI care and preventative . measures Key : Facts 13 of older adults are diagnosed with TBI , often from . falls Wealthier , healthier seniors are at higher risk of . TBI TBI can lead to serious conditions like dementia and cardiovascular . disease Source : UCSF Some 13 of older adults are diagnosed with traumatic brain injury TBI according to a study by UC San Francisco and the San
Activating Brain’s Serotonin Center Alters Behavior and Motivation Featured Neuroscience May 31, 2024 Summary : Stimulating the brain’s serotonin center , the dorsal raphe nucleus DRN activates areas responsible for behavior and motivation . This discovery , using opto-functional MRI in awake mice , highlights serotonin’s significant role in cognitive . functions The study offers insights into how serotonin influences behavior and mood . regulation Key : Facts DRN serotonin activation stimulates the cerebral cortex and basal . ganglia High-field MRI and optogenetics reveal brain-wide effects of serotonin in awake . mice Findings could advance understanding of mood disorders and behavioral . adaptations Source : OIST Our brains are made of tens of billions of nerve cells called neurons .
Ketones May Help Reverse Cognitive Decline Featured Neurology Neuroscience May 31, 2024 Summary : As we age , our brain naturally becomes more insulin resistant , disrupting neuron communication and leading to cognitive decline and . neurodegeneration Researchers studied how acute insulin resistance impacts neuronal function before symptoms of chronic conditions like Alzheimer’s manifest . Using mice models , they found that ketones could restore impaired synaptic activity , axonal conduction , and network . synchronization This research highlights potential ketone-based therapies for neurodegenerative . diseases Key : Facts Acute insulin resistance in the brain impairs synaptic activity , axonal conduction , and network . synchronization Administering ketones like D-βHb can restore these
: How Not’ Changes Everything : Brain Interprets Negated Adjectives Featured Neuroscience Open Neuroscience Articles May 30, 2024 Summary : Researchers found that negating adjectives with not” affects how our brains interpret their meaning , mitigating rather than inverting their definition . In lab-based experiments , participants took longer to process phrases like not bad” compared to good” or bad . 8221 Brain imaging showed initial interpretations of negated adjectives were similar to their affirmative counterparts but weakened . These findings help us understand how the brain processes negation and other complex linguistic . operations Key : Facts Negated adjectives are processed more slowly and with more varied . interpretations Initial brain activity for negated adjectives is